Six steps for administration1
Check Expiration date. Product must be used before the date on sprayer label.
Remove rubber tip protector. Do not remove dose-divider clip at the other end of the sprayer.
With the patient in an upright position, place the tip just inside the nostril to ensure FluMist Quadrivalent is delivered into the nose.
With a single motion, depress plunger as rapidly as possible until the dose-divider clip prevents you from going further.
Pinch and remove the dose-divider clip from the plunger.
Place the tip just inside the other nostril and with a single motion, depress plunger as rapidly as rapidly as possible to deliver remaining vaccine.
Dispose of sprayer per standard procedures (eg, sharps container).
Your patients may have misconceptions about receiving FluMist Quadrivalent—and may need your help to clarify
FluMist Quadrivalent is contraindicated in persons who have had a severe allergic reaction (e.g., anaphylaxis) to any vaccine component, including egg protein, or after a previous dose of any influenza vaccine, and in children and adolescents receiving concomitant aspirin or aspirin-containing therapy.
In clinical trials, the risks of hospitalization and wheezing were increased in children <24 months of age who received trivalent FluMist® (Influenza Vaccine Live, Intranasal).
Children <5 years of age with recurrent wheezing and persons of any age with asthma may be at increased risk of wheezing following FluMist Quadrivalent administration. FluMist Quadrivalent has not been studied in persons with severe asthma or active wheezing.
If Guillain-Barré syndrome has occurred within 6 weeks of any prior influenza vaccination, the decision to give FluMist Quadrivalent should be based on careful consideration of the potential benefits and risks.
FluMist Quadrivalent has not been studied in immunocompromised persons.
The safety of FluMist Quadrivalent in individuals with underlying medical conditions predisposing them to wild-type influenza infection complications has not been established.
FluMist Quadrivalent may not protect all individuals receiving the vaccine.
The most common solicited adverse reactions (occurring ≥10% in vaccine recipients and at least 5% greater than in placebo) reported after FluMist were runny nose or nasal congestion in all persons 2-49 years, fever >100°F in children 2-6 years, and sore throat in adults 18-49 years. Among children 2-17 years who received FluMist Quadrivalent, 32% reported runny nose or nasal congestion and 7% reported fever >100°F. Among adults 18-49 years who received FluMist Quadrivalent, 44% reported runny nose or nasal congestion and 19% reported sore throat.
FluMist® Quadrivalent (Influenza Vaccine Live, Intranasal) is a vaccine indicated for active immunization of persons 2-49 years of age for the prevention of influenza disease caused by influenza A subtype viruses and type B viruses contained in the vaccine. FluMist Quadrivalent is for intranasal administration only.
Please see full Prescribing Information for FluMist Quadrivalent, including Patient Information.